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Thermal Design Optimization of Shell-and-Tube Heat Exchanger Liquid to Liquid to Minimize Cost using Combination Bell-Delaware Method and Genetic Algorithm

Shell-and-tube heat exchanger is designed to satisfy certain requirements such as heat transfer GJB2 mutation spectrum in 2063 Chinese patients with nonsyndromic hearing impairment capability, allowable pressure drop and limitation of size.Beside such requirements, it is important to consider economical point of view to get the lowest total cost.In

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